Gene Symbol | RTR1 |
Entrez Gene ID | 856882 |
Full Name | RNA polymerase II subunit B1 CTD phosphatase RTR1 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
ORF » Species Summary » Saccharomyces cerevisiae S288C » RTR1 cDNA ORF clone
Gene Symbol | RTR1 |
Entrez Gene ID | 856882 |
Full Name | RNA polymerase II subunit B1 CTD phosphatase RTR1 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
mRNA | Protein | Name |
---|---|---|
NM_001179029.3 | NP_011066.3 | RNA polymerase II subunit B1 CTD phosphatase RTR1 |
Saccharomyces cerevisiae (baker's yeast) | RTR1 | NP_011066.3 |
Eremothecium gossypii | AGOS_AFR175C | NP_985722.1 |
Kluyveromyces lactis | KLLA0F12672g | XP_455653.1 |
The nucleotide sequence of Saccharomyces cerevisiae chromosome V.
Dietrich FS, Mulligan J, Hennessy K, Yelton MA, Allen E, Araujo R, Aviles E, Berno A, Brennan T, Carpenter J, Chen E, Cherry JM, Chung E, Duncan M, Guzman E, Hartzell G, Hunicke-Smith S, Hyman RW, Kayser A, Komp C, Lashkari D, Lew H, Lin D, Mosedale D, Davis RW
Nature387(6632 Suppl)78-81(1997 May)
Life with 6000 genes.
Goffeau A, Barrell BG, Bussey H, Davis RW, Dujon B, Feldmann H, Galibert F, Hoheisel JD, Jacq C, Johnston M, Louis EJ, Mewes HW, Murakami Y, Philippsen P, Tettelin H, Oliver SG
Science (New York, N.Y.)274(5287)546, 563-7(1996 Oct)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Findings show that Rtr1 is a global regulator of the C-terminal domain (CTD) code with deletion of RTR1 causing genome-wide changes in Ser5-P CTD phosphorylation and cotranscriptional histone H3 lysine 36 trimethylation.
Title: Phosphatase Rtr1 Regulates Global Levels of Serine 5 RNA Polymerase II C-Terminal Domain Phosphorylation and Cotranscriptional Histone Methylation.
Rtr1p may imprint its RNA targets cotranscriptionally and determine their downstream degradation mechanism by directing these transcripts to a novel turnover pathway that involves Rtr1p, Dhh1p, and the REX family of exonucleases.
Title: The Rtr1p CTD phosphatase autoregulates its mRNA through a degradation pathway involving the REX exonucleases.
Data indicate that the structure of the phosphoryl transfer domain and reaction mechanism for the phosphoryl transfer activity of regulator of transcription 1 (Rtr1) is distinct from those of other phosphatase families.
Title: Structure of Saccharomyces cerevisiae Rtr1 reveals an active site for an atypical phosphatase.
Studies revealed that hyperphosphorylated RNAPII is the primary interacting partner for Rtr1.
Title: The interactome of the atypical phosphatase Rtr1 in Saccharomyces cerevisiae.
Rtr1 functions as a CTD phosphatase essential for the Serine5-to-Serine2-Phosphorylation transition.
Title: Rtr1 is a CTD phosphatase that regulates RNA polymerase II during the transition from serine 5 to serine 2 phosphorylation.
The following RTR1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the RTR1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSi05634 | |
Clone ID Related Accession (Same CDS sequence) | NM_001179029.3 | |
Accession Version | NM_001179029.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 681bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-31 | |
Organism | Saccharomyces cerevisiae S288C | |
Product | RNA polymerase II subunit B1 CTD phosphatase RTR1 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by SGD. This record is derived from an annotated genomic sequence (NC_001137). On Jul 30, 2012 this sequence version replaced NM_001179029.2. ##Genome-Annotation-Data-START## Annotation Provider :: SGD Annotation Status :: Full Annotation Annotation Version :: R64-2-1 URL :: http://www.yeastgenome.org/ ##Genome-Annotation-Data-END## COMPLETENESS: incomplete on both ends. |
1 | ATGGCGACGA TTGAAGATAT TAAGGAAACG GCGTTAATCC CTTTCCAAAA GCACAGGCAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_011066.3 |
CDS | 1..681 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001179029.3 |
1 | ATGGCGACGA TTGAAGATAT TAAGGAAACG GCGTTAATCC CTTTCCAAAA GCACAGGCAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
The nucleotide sequence of Saccharomyces cerevisiae chromosome V. |
Life with 6000 genes. |