Gene Symbol | SGT1 |
Entrez Gene ID | 854222 |
Full Name | co-chaperone SGT1 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
ORF » Species Summary » Saccharomyces cerevisiae S288C » SGT1 cDNA ORF clone
Gene Symbol | SGT1 |
Entrez Gene ID | 854222 |
Full Name | co-chaperone SGT1 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
mRNA | Protein | Name |
---|---|---|
NM_001183476.1 | NP_014700.1 | co-chaperone SGT1 |
Kluyveromyces lactis | KLLA0F16302g | XP_455814.1 |
Eremothecium gossypii | AGOS_AAR138C | NP_982680.1 |
Schizosaccharomyces pombe (fission yeast) | git7 | NP_595340.1 |
Saccharomyces cerevisiae (baker's yeast) | SGT1 | NP_014700.1 |
The nucleotide sequence of Saccharomyces cerevisiae chromosome XV.
Dujon B, Albermann K, Aldea M, Alexandraki D, Ansorge W, Arino J, Benes V, Bohn C, Bolotin-Fukuhara M, Bordonn? R, Boyer J, Camasses A, Casamayor A, Casas C, Ch?ret G, Cziepluch C, Daignan-Fornier B, Dang DV, de Haan M, Delius H, Durand P, Fairhead C, Feldmann H, Gaillon L, Kleine K
Nature387(6632 Suppl)98-102(1997 May)
Life with 6000 genes.
Goffeau A, Barrell BG, Bussey H, Davis RW, Dujon B, Feldmann H, Galibert F, Hoheisel JD, Jacq C, Johnston M, Louis EJ, Mewes HW, Murakami Y, Philippsen P, Tettelin H, Oliver SG
Science (New York, N.Y.)274(5287)546, 563-7(1996 Oct)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Report the importance of Hsp90/Sgt1 system in controlling cell plasticity.
Title: The Plasticity of the Hsp90 Co-chaperone System.
overexpression of other co-chaperones further disrupts the essential functions of Cns1 and Sgt1. However, the specificity of the negative effects indicates that only a subset of co-chaperones competes with Sgt1 or Cns1 for binding to Hsp90.
Title: Mutation of essential Hsp90 co-chaperones SGT1 or CNS1 renders yeast hypersensitive to overexpression of other co-chaperones.
protein kinase CK2 phosphorylates Ser(361) on Sgt1, and this phosphorylation inhibits Sgt1 dimerization
Title: Sgt1 dimerization is negatively regulated by protein kinase CK2-mediated phosphorylation at Ser361.
Sgt1 dimerization is required for kinetochore assembly.
Title: Sgt1 dimerization is required for yeast kinetochore assembly.
Sgt1p acts as a "client adaptor" recruiting specific clients to Hsp82p co-chaperone complexes
Title: Sgt1p is a unique co-chaperone that acts as a client adaptor to link Hsp90 to Skp1p.
The following SGT1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SGT1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSi03365 | |
Clone ID Related Accession (Same CDS sequence) | NM_001183476.1 | |
Accession Version | NM_001183476.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1188bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-31 | |
Organism | Saccharomyces cerevisiae S288C | |
Product | co-chaperone SGT1 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by SGD. This record is derived from an annotated genomic sequence (NC_001147). ##Genome-Annotation-Data-START## Annotation Provider :: SGD Annotation Status :: Full Annotation Annotation Version :: R64-2-1 URL :: http://www.yeastgenome.org/ ##Genome-Annotation-Data-END## COMPLETENESS: incomplete on both ends. |
1 | ATGCCTGTTG AAAAAGATTT AAAAACTGCC TACAAAGCTT TGTATGATGA GAAGGAACCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_014700.1 |
CDS | 1..1188 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001183476.1 |
1 | ATGCCTGTTG AAAAAGATTT AAAAACTGCC TACAAAGCTT TGTATGATGA GAAGGAACCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
The nucleotide sequence of Saccharomyces cerevisiae chromosome XV. |
Life with 6000 genes. |