VTA1 cDNA ORF clone, Saccharomyces cerevisiae S288C

The nucleotide sequence of Saccharomyces cerevisiae chromosome XII.
Johnston M, Hillier L, Riles L, Albermann K, Andr? B, Ansorge W, Benes V, Br?ckner M, Delius H, Dubois E, D?sterh?ft A, Entian KD, Floeth M, Goffeau A, Hebling U, Heumann K, Heuss-Neitzel D, Hilbert H, Hilger F, Kleine K, K?tter P, Louis EJ, Messenguy F, Mewes HW, Hoheisel JD
Nature387(6632 Suppl)87-90(1997 May)

Life with 6000 genes.
Goffeau A, Barrell BG, Bussey H, Davis RW, Dujon B, Feldmann H, Galibert F, Hoheisel JD, Jacq C, Johnston M, Louis EJ, Mewes HW, Murakami Y, Philippsen P, Tettelin H, Oliver SG
Science (New York, N.Y.)274(5287)546, 563-7(1996 Oct)

ESCRT-III binding to the Vta1 microtubule interacting and trafficking domains relieves linker region autoinhibition of the VSE to produce maximal activation of Vps4 during ESCRT function.
Title: Relief of autoinhibition enhances Vta1 activation of Vps4 via the Vps4 stimulatory element.

Structural basis of molecular recognition between ESCRT-III-like protein Vps60 and AAA-ATPase regulator Vta1 in the multivesicular body pathway.
Title: Structural basis of molecular recognition between ESCRT-III-like protein Vps60 and AAA-ATPase regulator Vta1 in the multivesicular body pathway.

models in which Vps4p MIT and Vta1p domains engage endosomal sorting complex required for transport-III substrates above the bowl and help transfer them into the bowl to be pumped through the center of the dodecameric assembly
Title: Cryo-EM structure of dodecameric Vps4p and its 2:1 complex with Vta1p.

impact of Vta1 and ESCRT-III family members on Vps4 ATPase activity
Title: ESCRT-III family members stimulate Vps4 ATPase activity directly or via Vta1.

mechanism of regulation by Vta1 in which the C-terminal domain stabilizes the ATP-dependent double ring assembly.
Title: Structural basis of Vta1 function in the multivesicular body sorting pathway.