ORF » Species Summary » Rattus norvegicus » Reactome

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Rattus norvegicus (Norway rat)

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Chaperonin-mediated protein folding Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus
Attachment of GPI anchor to uPAR Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
Transport to the Golgi and subsequent modification N-glycan trimming and elongation in the cis-Golgi
Reactions specific to the complex N-glycan synthesis pathway Incretin synthesis, secretion, and inactivation
PERK regulates gene expression Glucose metabolism
Glycolysis Gluconeogenesis
Fructose catabolism Galactose catabolism
A tetrasaccharide linker sequence is required for GAG synthesis Chondroitin sulfate/dermatan sulfate metabolism
Synthesis of IPs in the nucleus Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
Synthesis of very long-chain fatty acyl-CoAs Beta oxidation of palmitoyl-CoA to myristoyl-CoA
Beta oxidation of myristoyl-CoA to lauroyl-CoA Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA
Beta oxidation of butanoyl-CoA to acetyl-CoA Synthesis of Ketone Bodies
Alpha-oxidation of phytanate Cholesterol biosynthesis via lathosterol
Regulation of cholesterol biosynthesis by SREBP (SREBF) Activation of gene expression by SREBF (SREBP)
Synthesis of bile acids and bile salts via 27-hydroxycholesterol Recycling of bile acids and salts
Phospholipid metabolism Acyl chain remodelling of PE
Acyl chain remodelling of PS Synthesis of PI
Acyl chain remodelling of PI Synthesis of PG
Acyl chain remodelling of PG Synthesis of CL
Synthesis of PIPs at the late endosome membrane alpha-linolenic acid (ALA) metabolism
Synthesis of 12-eicosatetraenoic acid derivatives Synthesis of Hepoxilins (HX) and Trioxilins (TrX)
Sphingolipid metabolism Ubiquinol biosynthesis
PKA-mediated phosphorylation of key metabolic factors PP2A-mediated dephosphorylation of key metabolic factors
NOSTRIN mediated eNOS trafficking Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
Citric acid cycle (TCA cycle) Interconversion of 2-oxoglutarate and 2-hydroxyglutarate
The fatty acid cycling model Purine ribonucleoside monophosphate biosynthesis
Phosphate bond hydrolysis by NUDT proteins Vitamin C (ascorbate) metabolism
Vitamin B1 (thiamin) metabolism Vitamin B2 (riboflavin) metabolism
Coenzyme A biosynthesis Nicotinamide salvaging
Metabolism of amino acids and derivatives Amino acid synthesis and interconversion (transamination)
Tryptophan catabolism Methionine salvage pathway
Glyoxylate metabolism and glycine degradation Sulfur amino acid metabolism
Metabolism of porphyrins Biological oxidations
COX reactions Glucuronidation
Acetylation Conjugation of carboxylic acids
Erythrocytes take up carbon dioxide and release oxygen Response to metal ions
Metallothioneins bind metals Mitophagy
Platelet homeostasis Reduction of cytosolic Ca++ levels
ADP signalling through P2Y purinoceptor 12 Thromboxane signalling through TP receptor
Integrin alphaIIb beta3 signaling p130Cas linkage to MAPK signaling for integrins
Effects of PIP2 hydrolysis Response to elevated platelet cytosolic Ca2+
Disinhibition of SNARE formation Dissolution of Fibrin Clot
Basigin interactions Assembly of the pre-replicative complex
Orc1 removal from chromatin CDK-mediated phosphorylation and removal of Cdc6
DNA strand elongation Leading Strand Synthesis
Chromatin modifying enzymes HATs acetylate histones
DNA Repair Base-Excision Repair, AP Site Formation
Depurination Displacement of DNA glycosylase by APEX1
Termination of translesion DNA synthesis Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks
Processing of DNA double-strand break ends Presynaptic phase of homologous DNA pairing and strand exchange
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