TSHR Antibody (M22HC)

TSHR Antibody (M22HC)

The thyrotropin receptor (TSHR) is the major autoantigen in autoimmune hyperthyroidism. TSHR autoantibodies, acting as TSHR agonists (TRAb), are responsible for Graves’ disease. Measurement of TRAb is important for therapeutic and prognostic purposes.
V29001
¥76,643.00

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Description

The thyrotropin receptor (TSHR) is the major autoantigen in autoimmune hyperthyroidism. TSHR autoantibodies, acting as TSHR agonists (TRAb), are responsible for Graves’ disease. Measurement of TRAb is important for therapeutic and prognostic purposes.

Note

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Overview
Subclass IgG1
Conjugation Unconjugated
Antigen Species Human

Properties
Production Cultured in vitro under conditions free from animal-derived components
Purification Protein A/G affinity column
Formulation 50 mM Na-citrate, 150 mM NaCl, pH 7.0, containing 0.03% Proclin 300
Clone ID M22HC
Storage For up to three months at 2-8°C or for up to three years at -25°C~-15°C. Avoid repeated freezing and thawing.


Background
Target Background The thyrotropin receptor (TSHR) is the major autoantigen in autoimmune hyperthyroidism. TSHR autoantibodies, acting as TSHR agonists (TRAb), are responsible for Graves’ disease. Measurement of TRAb is important for therapeutic and prognostic purposes.