Beta-amyloid (1-42) Antibody (6E8), mAb, Mouse

Beta-amyloid (1-42) Antibody (6E8), mAb, Mouse

Beta-amyloid (Aβ or Abeta) are peptides of 36–43 amino acids. They are derived from the amyloid precursor protein (APP) by beta secretase and gamma secretase in human brain. Beta-amyloid 1-42 and Beta-amyloid 1- 40 are related to Alzheimer's disease (AD).
V28702
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Overview
Specificity
Substance 25G13 6E8 A40
Beta-amyloid (1–42) + + -
Beta-amyloid (1–40) - + +
Amyloid precursor protein - - -
Note:”+” means reaction, “-“ means no cross-reactivity
Clone ID 6E8
Epitope
Clone Epitope mapping
25G13 33–42
6E8 1–7
A40 35–40
Isotype IgG2b for mAb 6E8

Properties
Production Cultured in vitro under conditions free from animal-derived components
Purification Protein A/G affinity column
Formulation 50 mM Na-citrate, 150 mM NaCl, pH 7.0, containing 0.03% ProClin 300.
Storage For long term storage, aliquot and store at -25°C~-15°C or below. Avoid repeated freezing and thawing cycles.
Note GenScript can customize this product per customer's request including product size, buffer components, etc.

Applications
Platform Capture Detection Analyte
CLIA 6E8 25G13 Beta-amyloid 1–42
A40 6E8 Beta-amyloid 1–40

Background
Target Background Beta-amyloid (Aβ or Abeta) are peptides of 36–43 amino acids. They are derived from the amyloid precursor protein (APP) by beta secretase and gamma secretase in human brain. Beta-amyloid 1-42 and Beta-amyloid 1- 40 are related to Alzheimer's disease (AD).

For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.