PSA Antibody (8A12), mAb, Mouse

PSA (8A12), mAb, Mouse

Prostate specific antigen (PSA) is a serine protease produced by the prostate gland. In serum, it exists in different forms, cPSA, mainly including PSA-ACT (alpha-1-antichymotrypsin) and PSA-A2M (alpha-2-macroglobulin), fPSA (free PSA), etc. The blood level of PSA is increased in men with prostate cancer and it is considered as an indicator for prostate cancer, tumor recurrence and response to therapy.
V07301
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Description

Prostate specific antigen (PSA) is a serine protease produced by the prostate gland. In serum, it exists in different forms, cPSA, mainly including PSA-ACT (alpha-1-antichymotrypsin) and PSA-A2M (alpha-2-macroglobulin), fPSA (free PSA), etc. The blood level of PSA is increased in men with prostate cancer and it is considered as an indicator for prostate cancer, tumor recurrence and response to therapy.
Note

GenScript can customize this product per customer's request including product size, buffer components, etc.

Overview
Subclass IgG1
Host Species Mouse
Conjugation Unconjugated
Antigen Species Human

Properties
Production Cultured in vitro under conditions free from animal-derived components
Purification Protein A/G affinity column
Formulation 1) PBS, pH 7.4, containing 0.03% Proclin 300
2) 50 mM Na-citrate, 150 mM NaCl, pH 7.0, containing 0.03% Proclin 300 *
*: For new batch since 09/01/2018, please refer to COA.
Concentration ≥2mg/ml
Clone ID 8A12
Recommended pairs CLIA (Capture-Detection):
8A12 - 7H2
Sandwich immunoassay (Capture-Detection):
7H2 - 8A12
Storage For long term storage, aliquot and store at -20°C or below. Avoid repeated freezing and thawing cycles.

Applications
CLIA, LFIA, ELISA

Background
Target Background Prostate specific antigen (PSA) is a serine protease produced by the prostate gland. In serum, it exists in different forms, cPSA, mainly including PSA-ACT (alpha-1-antichymotrypsin) and PSA-A2M (alpha-2-macroglobulin), fPSA (free PSA), etc. The blood level of PSA is increased in men with prostate cancer and it is considered as an indicator for prostate cancer, tumor recurrence and response to therapy.