REST Antibody, mAb, Rabbit
REST Antibody, MAb, Rabbit

Western blot analysis of REST / NRSF expression in HeLa cell lysate.

REST Antibody, mAb, Rabbit

Transcriptional repressor which binds neuron-restrictive silencer element (NRSE) and represses neuronal gene transcription in non-neuronal cells. Restricts the expression of neuronal genes by associating with two distinct corepressors, mSin3 and CoREST, which in turn recruit histone deacetylase to the promoters of REST-regulated genes.
A03891
¥37,309.00

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Overview
Specificity This product is specific to REST
Host Species Rabbit
Immunogen A synthesized peptide derived from human REST
Species Reactivity Human
Conjugate Unconjugated

Applications
Working concentrations for specific applications should be determined by the investigators. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product.
Application Recommended Usage
Western Blot 1:1000-1:2000

Properties
Form Liquid
Storage Buffer Supplied in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
Storage Instructions Store at -20°C. This product is stable for 1 year upon receipt, when handled and stored as instructed.
Purification Affinity-chromatography
Isotype Rabbit IgG
Clonality Monoclonal

Examples
  • REST Antibody, MAb, Rabbit
    • REST Antibody, MAb, Rabbit

    Western blot analysis of REST / NRSF expression in HeLa cell lysate.


Background
Target Background Transcriptional repressor which binds neuron-restrictive silencer element (NRSE) and represses neuronal gene transcription in non-neuronal cells. Restricts the expression of neuronal genes by associating with two distinct corepressors, mSin3 and CoREST, which in turn recruit histone deacetylase to the promoters of REST-regulated genes.
Synonyms NRSF; RE1 silencing transcription factor; Repressor binding to the X2 box; rest; X2 box repressor; XBR;

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.