Insulin receptor Antibody, mAb, Rabbit
Insulin Receptor Antibody, MAb, Rabbit

Western blot analysis of Insulin Receptor expression in HeLa cell lysate.

Insulin receptor Antibody, mAb, Rabbit

Receptor tyrosine kinase which mediates the pleiotropic actions of insulin. Binding of insulin leads to phosphorylation of several intracellular substrates, including, insulin receptor substrates (IRS1, 2, 3, 4), SHC, GAB1, CBL and other signaling intermediates.
A03186
¥37,309.00

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Overview
Specificity This product is specific to Insulin receptor
Host Species Rabbit
Immunogen A synthesized peptide derived from human Insulin receptor
Species Reactivity Human; Mouse; Rat
Conjugate Unconjugated

Applications
Working concentrations for specific applications should be determined by the investigators. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product.
Application Recommended Usage
Western Blot 1:1000-1:2000
Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50-1:200

Properties
Form Liquid
Storage Buffer Supplied in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
Storage Instructions Store at -20°C. This product is stable for 1 year upon receipt, when handled and stored as instructed.
Purification Affinity-chromatography
Isotype Rabbit IgG
Clonality Monoclonal

Examples
  • Insulin Receptor Antibody, MAb, Rabbit
    • Insulin Receptor Antibody, MAb, Rabbit

    Western blot analysis of Insulin Receptor expression in HeLa cell lysate.


Background
Target Background Receptor tyrosine kinase which mediates the pleiotropic actions of insulin. Binding of insulin leads to phosphorylation of several intracellular substrates, including, insulin receptor substrates (IRS1, 2, 3, 4), SHC, GAB1, CBL and other signaling intermediates.
Synonyms CD220; HHF5; human insulin receptor; Insr; Insulin receptor subunit beta; IR 1; IR;

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.