p-p70 S6 Kinase (T421/S424) Antibody, mAb, Rabbit
P-p70 S6 Kinase (T421/S424) Antibody, MAb, Rabbit

Western blot analysis of SK61 phosphorylation expression in HEK293 cell lysate.

p-p70 S6 Kinase (T421/S424) Antibody, mAb, Rabbit

Acts to integrate nutrient and growth factor signals in regulation of protein synthesis, cell proliferation, cell growth, cell cycle progression and cell survival. Downstream effector of the mTOR signaling pathway.
A02655
¥37,309.00

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Overview
Specificity This product is specific to p-p70 S6 Kinase (T421/S424)
Host Species Rabbit
Immunogen A synthesized peptide derived from human p70 S6 Kinase around the phosphorylation site of T421/S424
Species Reactivity Human; Rat
Conjugate Unconjugated

Applications
Working concentrations for specific applications should be determined by the investigators. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product.
Application Recommended Usage
Western Blot 1:1000-1:2000
Immunoprecipitation (IP) 1:20-1:50

Properties
Form Liquid
Storage Buffer Supplied in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
Storage Instructions Store at -20°C. This product is stable for 1 year upon receipt, when handled and stored as instructed.
Purification Affinity-chromatography
Isotype Rabbit IgG
Clonality Monoclonal

Examples
  • P-p70 S6 Kinase (T421/S424) Antibody, MAb, Rabbit
    • P-p70 S6 Kinase (T421/S424) Antibody, MAb, Rabbit

    Western blot analysis of SK61 phosphorylation expression in HEK293 cell lysate.


Background
Target Background Acts to integrate nutrient and growth factor signals in regulation of protein synthesis, cell proliferation, cell growth, cell cycle progression and cell survival. Downstream effector of the mTOR signaling pathway.
Synonyms EC 2.7.11.1, KS6B1, P70-S6K, RPS6KB1, Ribosomal protein S6 kinase, Ribosomal protein S6 kinase, 70kDa, polypeptide 1, S6K, kinase p70S6K, p70-S6K

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.