p-p95 NBS1 (S343) Antibody, mAb, Rabbit
P-p95 NBS1 (S343) Antibody, MAb, Rabbit

Western blot analysis of p95/NBS1 phosphorylation expression in Jurkat cell lysate treated with Etopside.

p-p95 NBS1 (S343) Antibody, mAb, Rabbit

Component of the MRN complex, which plays a central role in double-strand break (DSB) repair, DNA recombination, maintenance of telomere integrity and meiosis. The MRN complex is involved in the repair of DNA double-strand breaks (DSBs) via homologous recombination (HR), an error-free mechanism which primarily occurs during S and G2 phases.
A02650
¥37,309.00

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Overview
Specificity This product is specific to p-p95 NBS1 (S343)
Host Species Rabbit
Immunogen A synthesized peptide derived from human p95 NBS1 around the phosphorylation site of S343
Species Reactivity Human
Conjugate Unconjugated

Applications
Working concentrations for specific applications should be determined by the investigators. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product.
Application Recommended Usage
Western Blot 1:1000-1:2000
Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50-1:200
Immunoprecipitation (IP) 1:20-1:50

Properties
Form Liquid
Storage Buffer Supplied in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
Storage Instructions Store at -20°C. This product is stable for 1 year upon receipt, when handled and stored as instructed.
Purification Affinity-chromatography
Isotype Rabbit IgG
Clonality Monoclonal

Examples
  • P-p95 NBS1 (S343) Antibody, MAb, Rabbit
    • P-p95 NBS1 (S343) Antibody, MAb, Rabbit

    Western blot analysis of p95/NBS1 phosphorylation expression in Jurkat cell lysate treated with Etopside.


Background
Target Background Component of the MRN complex, which plays a central role in double-strand break (DSB) repair, DNA recombination, maintenance of telomere integrity and meiosis. The MRN complex is involved in the repair of DNA double-strand breaks (DSBs) via homologous recombination (HR), an error-free mechanism which primarily occurs during S and G2 phases.
Synonyms Cell cycle regulatory protein P95, NBN, NBS, NIBRIN, NIJMEGEN BREAKAGE syndrome protein 1, p95-NBS1

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.