p57 Kip2 Antibody, mAb, Rabbit
P57 Kip2 Antibody, MAb, Rabbit

Western blot analysis on HeLa cell using p57 Kip2 Antibody, mAb, Rabbit.

p57 Kip2 Antibody, mAb, Rabbit

Potent tight-binding inhibitor of several G1 cyclin/CDK complexes (cyclin E-CDK2, cyclin D2-CDK4, and cyclin A-CDK2) and, to lesser extent, of the mitotic cyclin B-CDC2. Negative regulator of cell proliferation. May play a role in maintenance of the non-proliferative state throughout life.
A02643
¥37,309.00

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Overview
Specificity This product is specific to p57 Kip2
Host Species Rabbit
Immunogen A synthesized peptide derived from human p57 Kip2
Species Reactivity Human; Mouse; Rat
Conjugate Unconjugated

Applications
Working concentrations for specific applications should be determined by the investigators. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product.
Application Recommended Usage
Western Blot 1:1000-1:2000
Immunohistochemistry (IHC) 1:100-1:200
Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50-1:200
Immunohistochemistry Frozen (IHF) 1:50-1:200
Immunoprecipitation (IP) 1:20-1:50

Properties
Form Liquid
Storage Buffer Supplied in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
Storage Instructions Store at -20°C. This product is stable for 1 year upon receipt, when handled and stored as instructed.
Purification Affinity-chromatography
Isotype Rabbit IgG
Clonality Monoclonal

Examples
  • P57 Kip2 Antibody, MAb, Rabbit
    • P57 Kip2 Antibody, MAb, Rabbit

    Western blot analysis on HeLa cell using p57 Kip2 Antibody, mAb, Rabbit.


Background
Target Background Potent tight-binding inhibitor of several G1 cyclin/CDK complexes (cyclin E-CDK2, cyclin D2-CDK4, and cyclin A-CDK2) and, to lesser extent, of the mitotic cyclin B-CDC2. Negative regulator of cell proliferation. May play a role in maintenance of the non-proliferative state throughout life.
Synonyms BWCR; BWS; KIP2; WBS; p57; p57 Kip2; WBS ; CDKN1C; Cyclin dependent kinase inhibitor 1C

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.