Anti-Human CD8 Antibody (F002), mAb, Mouse
Anti-Human CD8 Antibody (F002), MAb, Mouse

Flow cytometric analysis of CD8 expression on human peripheral blood lymphocytes. Human PBMC stained with Anti-Human CD8 Antibody (F002), mAb, Mouse (GenScript, Cat. No. A02212. Red) or with mouse IgG1 isotype control (Gray), followed by goat anti-mouse IgG PE-conjugated antibody. Data shown was gated on CD3 (+)/SSCLow T lymphocytes.

Anti-Human CD8 Antibody (F002), mAb, Mouse

The product is specific for human CD8.
A02212
¥8,631.00

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Overview
Specificity The product is specific for human CD8.
Host Species Mouse
Immunogen Recombinant human CD8
Species Reactivity Human
Conjugate Unconjugated

Applications
Working concentrations for specific applications should be determined by the investigators. The suitability of this antibody for applications other than those listed below has not been determined. For flow cytometric staining, the following concentration range is recommended starting points for this product and is suggested that the reagent be titrated for optimal performance for each application.
Application Recommended Usage
Flow Cytometry ≤ 0.5 µg per million cells in 100 µl volume. It is strongly recommended that the reagent should be titrated for optimal performance for each application.

Properties
Form Liquid
Storage Buffer Supplied in 10 mM Sodium Citrate, 154 mM NaCl, pH 6.5.
Concentration 1 mg/ml
Storage Instructions The product remains stable up to 12 months at 4 °C from date of receipt. For longer time storage, store at -80 °C. Avoid repeated freeze-thaw cycles.
Purification Protein A affinity column
Isotype Mouse IgG1κ
Clonality Monoclonal
Note GenScript can customize this product per customer's request including conjugations, product size, buffer components, etc.

Examples
  • Anti-Human CD8 Antibody (F002), MAb, Mouse
    • Anti-Human CD8 Antibody (F002), MAb, Mouse

    Flow cytometric analysis of CD8 expression on human peripheral blood lymphocytes. Human PBMC stained with Anti-Human CD8 Antibody (F002), mAb, Mouse (GenScript, Cat. No. A02212. Red) or with mouse IgG1 isotype control (Gray), followed by goat anti-mouse IgG PE-conjugated antibody. Data shown was gated on CD3 (+)/SSCLow T lymphocytes.


Background
Target Background CD8 (cluster of differentiation 8) is a member of the immunoglobulin superfamily found on the majority of thymocytes, a subset of peripheral blood T cells, and NK cells (which express almost exclusively CD8a homodimers). CD8 antigen is existed as a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. CD8 acts as a co-receptor with MHC class I-restricted T cell receptors in antigen recognition and T cell activation and has been shown to play a role in thymic differentiation. CD8+ cytotoxic T cells are crucial for the killing of virus-infected cells and tumor cells.
Synonyms CD8; T-cell surface glycoprotein CD8

For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.