一次抗体と二次抗体-抗-エピトープタグ、免疫測定、Cas 9 » Primary Antibodies » 抗イディオタイプ抗体製品 » Anti-Bevacizumab Antibody (4H1), mAb, Mouse
Anti-Bevacizumab Antibody (4H1), MAb, Mouse

ELISA binding of Anti-Bevacizumab Antibody (4H1) (GenScript, A01975-40) with Bevacizumab. While the antibody does not recognize the human IgG (data not shown).Coating antigen: Bevacizumab, 1 µg/ml.
Anti-Bevacizumab Antibody (4H1) (GenScript, A01975-40) dilutions start from 1,000 ng/ml.
EC₅₀= 4.660 ng/ml.

Anti-Bevacizumab Antibody (4H1), MAb, Mouse

Standard curve of Bevacizumab Sandwich ELISA. The Bevacizumab Sandwich ELISA assay is developed by using Anti-Bevacizumab Antibody (4H1), mAb, Mouse (GenScript, A01975-40) and Anti-Bevacizumab Antibody (6C3), mAb, Mouse (GenScript, A01976-40) as the capture and detection antibodies, respectively
In this ELISA assay, Anti-Bevacizumab Antibody (6C3), mAb, Mouse (GenScript, A01976-40) was labeled with Biotin. GenScript can provide customized conjugation services for this product per customer's request.
The sensitivity is less than 78 pg/ml.

Anti-Bevacizumab Antibody (4H1), mAb, Mouse

The product is specific for Bevacizumab. The antibody is recommended as a capture antibody in a pharmacokinetic (PK) bridging assay with detection antibody GenScript, A01976-40, Anti-Bevacizumab Antibody (6C3), mAb, Mouse.
A01975
¥25,548.00

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Overview
Specificity The product is specific for Bevacizumab. The antibody is recommended as a capture antibody in a pharmacokinetic (PK) bridging assay with detection antibody GenScript, A01976-40, Anti-Bevacizumab Antibody (6C3), mAb, Mouse.
Host Species Mouse
Immunogen Bevacizumab
Conjugate Unconjugated

Applications
Working concentrations for specific applications should be determined by the investigators. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product.
Application Recommended Usage
ELISA 0.01-0.1 µg/ml

Properties
Form Lyophilized
Storage Buffer lyophilized with PBS, pH 7.4, containing 0.02% sodium azide.
Reconstitution Reconstitute the lyophilized powder with deionized water (or equivalent) to an final concentration of 0.5 mg/mL.
Storage Instructions The lyophilized product remains stable up to 1 year at -20 °C from date of receipt. Upon reconstitution, it can be stored for 2-3 weeks at 2-8 °C or for up to 12 months at -20 °C or below. Avoid freeze/thaw cycles.
Purification Protein A affinity column
Isotype Mouse IgG1
Clonality Monoclonal
Clone ID 4H1
Note GenScript can customize this product per customer's request including product size, buffer components, etc.

Examples
  • Anti-Bevacizumab Antibody (4H1), MAb, Mouse
    • Anti-Bevacizumab Antibody (4H1), MAb, Mouse

    ELISA binding of Anti-Bevacizumab Antibody (4H1) (GenScript, A01975-40) with Bevacizumab. While the antibody does not recognize the human IgG (data not shown).Coating antigen: Bevacizumab, 1 µg/ml.
    Anti-Bevacizumab Antibody (4H1) (GenScript, A01975-40) dilutions start from 1,000 ng/ml.
    EC₅₀= 4.660 ng/ml.

  • Anti-Bevacizumab Antibody (4H1), MAb, Mouse
    • Anti-Bevacizumab Antibody (4H1), MAb, Mouse

    Standard curve of Bevacizumab Sandwich ELISA. The Bevacizumab Sandwich ELISA assay is developed by using Anti-Bevacizumab Antibody (4H1), mAb, Mouse (GenScript, A01975-40) and Anti-Bevacizumab Antibody (6C3), mAb, Mouse (GenScript, A01976-40) as the capture and detection antibodies, respectively
    In this ELISA assay, Anti-Bevacizumab Antibody (6C3), mAb, Mouse (GenScript, A01976-40) was labeled with Biotin. GenScript can provide customized conjugation services for this product per customer's request.
    The sensitivity is less than 78 pg/ml.


Background
Target Background Bevacizumab (Avastin) is a humanized monoclonal antibody that is approved by the U.S. Food and Drug Administration for the treatment of a number of types of cancers and a specific eye disease. Bevacizumab binds to a continuous epitope in VEGF, preventing interaction of VEGF with VEGFR on the surface of endothelial cells. It can be used to inhibit solid tumour growth and metastasis by weakening tumour angiogenesis.Anti-Bevacizumab Antibody (4H1), mAb, Mouse is produced from a hybridoma resulting from the fusion of partner and B-lymphocytes obtained from a mouse immunized with Bevacizumab.
Synonyms Mouse monoclonal to Avastin

For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.